Prospective Study on Factors influencing Lymph Node Yield in Neck Dissection of Head and Neck Tumours

Prospective Study on Factors influencing Lymph Node Yield in Neck Dissection of Head and Neck Tumours - Lymph Node Yield in Neck Dissection

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00039131

Enrollment

200

Registered

2026-02-03

Start date

2025-12-11

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer in the head and neck area

Interventions

Group 1: This study investigates possible factors that influence lymph node yield during neck lymph node dissection in head and neck tumours. The study is a surgical study in which additional data is

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: -Head and neck tumour diagnosis -Capacity to give consent

Exclusion criteria

Exclusion criteria: -Patient age < 18 -Patient has no head and neck tumour diagnosis -Patient is not capable of giving consent

Design outcomes

Primary

Measure	Time frame
The lymph node yield is influenced by factors such as tumour stage, body weight, body mass index, previous radiation therapy, the surgeon's experience and the lymph node levels that have been cleared. The primary endpoint is to determine the number of lymph nodes per lymph node level after neck dissection as part of tumour therapy in the ENT area.	—

Secondary

Measure	Time frame
Secondary endpoints are to identify factors influencing lymph node yield, such as body height, body weight, operating time, surgeon experience and differentiation between elective, radical and revision neck dissection. Criteria such as ipsilateral or contralateral neck dissection are recorded. Tumour stage, location of the primary tumour, clinical and pathological TNM stage, grading and p16/HPV status influence the number of lymph node metastases. Lymph node levels are classified according to Robbins. Main criteria: - Gender - Age - Date of surgery - Incision-suture time of the neck dissection and entire operation - Height and weight - Clinical and pathological TNM stage with grading and p16/HPV status - Number of affected lymph nodes and total number of lymph nodes according to lymph node level according to Robbins - Experience of the surgeon Secondary criteria: - Elective, radical or radical modified neck dissection - Suspicion of clinical lymph node metastases - Revision neck dissection - Anticoagulation/antiplatelet therapy - Previous neck surgery - Previous radiotherapy	—

Measure

Time frame

Secondary endpoints are to identify factors influencing lymph node yield, such as body height, body weight, operating time, surgeon experience and differentiation between elective, radical and revision neck dissection. Criteria such as ipsilateral or contralateral neck dissection are recorded. Tumour stage, location of the primary tumour, clinical and pathological TNM stage, grading and p16/HPV status influence the number of lymph node metastases. Lymph node levels are classified according to Robbins. Main criteria: - Gender - Age - Date of surgery - Incision-suture time of the neck dissection and entire operation - Height and weight - Clinical and pathological TNM stage with grading and p16/HPV status - Number of affected lymph nodes and total number of lymph nodes according to lymph node level according to Robbins - Experience of the surgeon Secondary criteria: - Elective, radical or radical modified neck dissection - Suspicion of clinical lymph node metastases - Revision neck dissection - Anticoagulation/antiplatelet therapy - Previous neck surgery - Previous radiotherapy

—

Countries

Germany

Contacts

Public ContactNicholas Bevis

Klinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsmedizin Göttingen

nicholas.bevis@med.uni-goettingen.de0551-39 64229

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026