Comparison of functional outcome in patients with rectal cancer after neoadjuvant radio(chemo)therapy and operation with patients after total neoadjuvant therapy and "watch and wait"

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00039114

Enrollment

Registered

2026-01-30

Start date

2026-03-09

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C20

Interventions

Group 1: Patients with rectal cancer treated by neoadjuvant radiochemotherapy and subsequent rectal resection and TME surgery Group 2: Patients wit rectal cancer treated by total neoadjuvant radiochem

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Diagnosis of rectal cancer - Treatment modalities a) neoadjuvant radiochemotherapy and operation b) total neoadjuvant therapy and watch-and-wait - informed consent

Exclusion criteria

Exclusion criteria: - palliative care - no informed consent possible - no anastomosis (terminal ostomy)

Design outcomes

Primary

Measure	Time frame
Defecation, incontinence and patient satisfaction are assessed at 6 and 12 months after initial therapy by questionnaire (LARS Score)	—

Secondary

Measure	Time frame
Duration of LARS-associated symptoms after therapy, comparison of outcome between laparoscopic and robotic low anterior rectum resection	—

Countries

Germany

Contacts

Public ContactSwantje Nickelsen

Medizinische Hochschule Hannover

nickelsen.swantje@mh-hannover.de+4917615322606

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026