Contrast-associated acute kidney injury (AKI) and deterioration of renal function, as well as iodine-induced thyroid dysfunction (especially hyperthyroidism/thyrotoxicosis up to thyrotoxic crisis) in the context of contrast-enhanced CT.
Conditions
Interventions
Group 1: Retrospective analysis of all patients at Heidelberg University Hospital who underwent contrast-enhanced CT with intravenous iodinated contrast during 07/2021–06/2023. Pseudonymized routine d
optional follow-up windows if available). No additional procedures and no patient contact. No study-related interventions
one-time extraction of routine data.
Group 2: Same data collection for 07/2023–06/2025 after implementation of the updated contrast SOP. Cohort comparison and within-window pre/post changes are assess
Sponsors
Universitätsklinkum Heidelberg
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Examination using iodinated contrast media.
Exclusion criteria
Exclusion criteria: No examination using iodinated contrast media.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depiction of a potential correlation between renal parameters/renal health and thyroid parameters/thyroid health in patients undergoing contrast-enhanced CT before and after implementation of the updated SOP for contrast media administration. Data collection is conducted through an analysis of the patient database. | — |
Secondary
| Measure | Time frame |
|---|---|
| Depiction of the trajectory of renal parameters over a patient’s hospital stay across multiple CT examinations. | — |
Countries
Germany
Contacts
Public ContactHendrik Voigtländer
Universitätsklikum Heidelberg
Outcome results
None listed