Impact of gonadotoxic therapies on fertility (FertiTOX). Distress factors of potential fertility impairments in oncology patients and resulting intrapersonal stress response – the significance of fertility preservation as a preventive measure

Impact of gonadotoxic therapies on fertility (FertiTOX). Distress factors of potential fertility impairments in oncology patients and resulting intrapersonal stress response – the significance of fertility preservation as a preventive measure - FertiTOX

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00039039

Enrollment

150

Registered

2026-01-28

Start date

2026-02-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C00-C97 Z08

Interventions

Group 1: Analysis of oncology patients with regard to various stress factors such as fertility distress, depression, coping, quality of life, fear of progression and others. Patients who have already

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: - Currently undergoing or having already completed potentially gonadotoxic therapy due to cancer - Aged between 18 and 45

Exclusion criteria

Exclusion criteria: - no potentially gonadotoxic treatment, for instance due to benign tumour

Design outcomes

Primary

Measure	Time frame
The aim of the study is to categorise distress profiles. These stress profiles will be based on various variables such as fertility distress, fertility-related quality of life, depression, anxiety, coping, quality of life, fear of progression, acceptance of illness and decision certainty. All questionnaires have already been sufficiently validated and used in renowned primary studies. Various control factors such as desire to have children, gender and existing children will also be included in the calculation. The survey will be conducted at a single point in time. The timing can vary throughout all stages of cancer and cancer treatment. The data will be collected using a web-based application (Unipark) and stored anonymously.	—

Measure

Time frame

The aim of the study is to categorise distress profiles. These stress profiles will be based on various variables such as fertility distress, fertility-related quality of life, depression, anxiety, coping, quality of life, fear of progression, acceptance of illness and decision certainty. All questionnaires have already been sufficiently validated and used in renowned primary studies. Various control factors such as desire to have children, gender and existing children will also be included in the calculation. The survey will be conducted at a single point in time. The timing can vary throughout all stages of cancer and cancer treatment. The data will be collected using a web-based application (Unipark) and stored anonymously.

—

Countries

Germany

Contacts

Public ContactTana Dornbrach

Universitätsklinikum Ulm, Klinik für Psychosomatische Medizin und Psychotherapie

tana.dornbrach@uni-ulm.de+49731-500-61933

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026