Investigation of age-related changes in muscle strength, muscle mass, and physical and cognitive performance in healthy adults aged 50 years and older within a preventive exercise and supplementation study.
Conditions
Interventions
Group 1: The intervention group will receive 5g of creatine daily for the first four weeks, followed by a placebo for the next four weeks. The supplements should be taken every morning after waking up
Sponsors
IST Hochschule für Management
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: All subjects should be at least 50 years old. They should not have any injuries or chronic illnesses that would be a contraindication for resistance training or creatine supplementation. In addition, they should not be taking any anabolic steroids or other medications that could influence resistance training or the effects of creatine.
Exclusion criteria
Exclusion criteria: Exclusion criteria: - Individuals who are unable to participate in the training at least twice per week. - Individuals taking medications that may affect creatine absorption or metabolism. - Individuals with liver diseases that could interfere with creatine metabolism. - Individuals with orthopedic or psychological conditions. - Individuals with organ diseases, in particular liver or kidney diseases, cardiovascular disorders, or a pacemaker, if these conditions contraindicate creatine supplementation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in muscle strength and body composition. Data will be collected before the intervention (baseline) and after eight weeks. Maximum strength will also be measured regularly during the intervention phase (every two weeks). Muscle strength: - One-repetition maximum on nine E-Gym machines - Handgrip strength measurement using a dynamometer - Chair rising test Body composition: - Bioimpedance analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in mobility, quality of life, cardiovascular parameters, and cognitive performance. Data will be collected before the start of the intervention and after eight weeks. Mobility will be assessed using the Timed Up and Go test. Quality of life will be assessed using a standardized questionnaire. Blood pressure will be measured as a physiological parameter. Cognitive performance will be assessed using a Flanker/Stroop test. | — |
Countries
Germany
Contacts
Public ContactTim Havers
IST Hochschule für Management
Outcome results
None listed