Idiopathic hypersomnia (ORPHA:33208)
Conditions
Interventions
Group 1: Patients aged between 18 and 75 with a diagnosed IHS (target recruitment: 24 participants) will be invited to take part in the study. Participants will be provided with six Salivettes to coll
Sponsors
Interdisziplinäres schlafmedizinisches Zentrum Lutherstadt Wittenberg
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with idiopathic hypersomnia in a sleep laboratory (exclusion criteria must not apply) 2) Healthy control group (exclusion criteria must not apply here either)
Exclusion criteria
Exclusion criteria: • Treatment for depression (with medication or psychotherapy) in the last twelve months • Insulin-dependent diabetes mellitus • Use of glucocorticoid medication in the last month • Moderate or severe obstructive sleep apnea syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Investigation of differences in the diurnal cortisol profile between patients with idiopathic hypersomnia and healthy control subjects as an indication of possible dysfunction of the HPA axis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Additional investigation - Frequency of abnormal cortisol levels in patients with IHS - Changes in the daily cortisol rhythm - Correlation between measured cortisol levels and symptoms in patients diagnosed with idiopathic hypersomnia | — |
Countries
Germany
Contacts
Public ContactChristian Veauthier
Interdisziplinäres schlafmedizinisches Zentrum Lutherstadt Wittenberg
Outcome results
None listed