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Automating MedicaL Protocols with LargE Language Models: A Feasibility Study with HeaRt Team Protocols

Automating MedicaL Protocols with LargE Language Models: A Feasibility Study with HeaRt Team Protocols - ALERT

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038946
Enrollment
250
Registered
2026-01-26
Start date
2026-01-27
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I35.0 I35.1 I34.0 I36.1

Interventions

Group 1: Manual generation of heart team protocols (mHT protocols) by physicians based on clinical and paraclinical patient data as the basis for therapy decisions in the Heart Team
measurement of time and correctness of data transfer (baseline). Group 2: Artificial intelligence based heart team protocols (aiHT protocols), which are generated using large language models, based on
measurement of time and the number of correct entries (baseline).

Sponsors

Deutsches Herzzentrum der Charité
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with a valvular heart disease capable of providing informed consent that are also intended for a heart team consultation.

Exclusion criteria

Exclusion criteria: Patients incapable of giving informed consent

Design outcomes

Primary

MeasureTime frame
Comparison of accuracy of AI-based heart team protocols (aiHT protocols) with and without manual correction with manual heart team protocols (mHT protocols) and information in medical reports using statistical methods (measurement of correct transfer using a scoring system).

Secondary

MeasureTime frame
Time required to create protocols for all three methods (mHT protocols, aiHT protocols with manual adjustment, and fully automatized aiHT protocols) as well as the learning curve (increasing efficiency in protocol assessment)

Countries

Germany

Contacts

Public ContactIsabel Mattig

Deutsches Herzzentrum der Charité

isabel.mattig@dhzc-charite.de+49 30 450 513 142

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026