Integration of CT-based coronary angiography into the cardiac catheterization workflow: impact on intervention an outcomes

Integration of CT-based coronary angiography into the cardiac catheterization workflow: impact on intervention an outcomes - CT-based coronary angiography/cardiac catheterization workflow

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038939

Enrollment

196

Registered

2026-01-12

Start date

2026-01-01

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I25.1

Interventions

Group 1: The results of the CT coronary angiography are available during the invasive coronary angiography via an integrated display (intervention arm). Group 2: The investigator reviews the CT corona

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Manifest coronary artery disease confirmed by CT coronary angiography with an indication for invasive coronary angiography - CT coronary angiography and invasive coronary angiography performed at GRN Clinic Weinheim - Capacity to provide informed consent

Exclusion criteria

Exclusion criteria: - Patients in whom, despite a positive CT angiography, no need for intervention is identified by invasive angiography or by coronary physiological assessment (iFR/RFR/FFR) - Lack of informed consent from the participants - Pregnant women, age < 18 years

Design outcomes

Primary

Measure	Time frame
- Need to change the guiding catheter - Need for lesion pre-treatment using rotational atherectomy or intravascular lithotripsy - Need for intravascular imaging using intravascular ultrasound (IVUS) - Length of the anticipated diseased vessel segments; number, diameter, and length of implanted stents - Occurrence of procedural complications (perforation, severe dissection, stent malapposition or underexpansion requiring post-dilatation, transient or permanent occlusion of the main vessel or side branch) - Troponin T increase (pre- vs. post-interventional) - Procedure duration, cumulative radiation exposure, and contrast agent volume - Length of hospital stay (days) - Composite endpoint (score 0–6): - Need for IVUS - Occurrence of at least one of the procedural complications listed above - Troponin T increase on the following day (>5-fold from baseline) - Contrast agent volume >200 mL - Radiation exposure >3 mSv - Hospital stay >1 day	—

Measure

Time frame

- Need to change the guiding catheter - Need for lesion pre-treatment using rotational atherectomy or intravascular lithotripsy - Need for intravascular imaging using intravascular ultrasound (IVUS) - Length of the anticipated diseased vessel segments; number, diameter, and length of implanted stents - Occurrence of procedural complications (perforation, severe dissection, stent malapposition or underexpansion requiring post-dilatation, transient or permanent occlusion of the main vessel or side branch) - Troponin T increase (pre- vs. post-interventional) - Procedure duration, cumulative radiation exposure, and contrast agent volume - Length of hospital stay (days) - Composite endpoint (score 0–6): - Need for IVUS - Occurrence of at least one of the procedural complications listed above - Troponin T increase on the following day (>5-fold from baseline) - Contrast agent volume >200 mL - Radiation exposure >3 mSv - Hospital stay >1 day

—

Secondary

Measure	Time frame
- Cardiac death, stent thrombosis, myocardial infarction, in-stent restenosis, and target lesion revascularization. All of the above events are assessed at 6, 12, and 24 months after the index procedure. - Standardized quality-of-life questionnaire (SAQ [Seattle Angina Questionnaire]-7 score) at 6, 12, and 24 months - Material consumption, material costs, and total treatment costs	—

Countries

Germany

Contacts

Public ContactGrigorios Korosoglou

GRN Klinik Weinheim

Grigorios.Korosoglou@grn.de06201 89-0

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026