Comparison of different therapeutic algorithms in late abortions - a retrospective study based on patient cohorts from two clinics

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00038903

Enrollment

2000

Registered

2026-05-29

Start date

2026-03-03

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

O06.9

Interventions

Group 1: Retrospective analysis of all female patients aged =18 years who were admitted to the Florence Nightingale Hospital Düsseldorf between January 1, 2015, and December 31, 2024, and who experien

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 11+0 - 23+6 gestational week

Exclusion criteria

Exclusion criteria: 23+6 gestational week

Design outcomes

Primary

Measure	Time frame
A site comparison with two study arms will be conducted by analyzing primary endpoints, including blood loss (delta hemoglobin), duration of hospital stay (in days), severe complications, and subsequent surgical interventions. All pregnancies in which an early or late miscarriage was diagnosed will be identified via a database query. The analysis is based on clinical data from the respective study sites and represents a purely retrospective study. Data extraction at University Hospital Münster will be performed by Kathrin Oelmeier, while data from Florence Nightingale Hospital Düsseldorf will be collected by Ralf Schmitz. After anonymization, the combined datasets from both institutions will be analyzed and evaluated by Luisa Guter. The following clinical parameters will be recorded: maternal age, gestational age at diagnosis, gestational age at miscarriage, diagnosis of miscarriage, obstetric history, hemoglobin levels before and after miscarriage, administration of antibiotics, severe complications, relevant maternal comorbidities, fetal genetic causes, and duration of hospital stay.	—

Measure

Time frame

A site comparison with two study arms will be conducted by analyzing primary endpoints, including blood loss (delta hemoglobin), duration of hospital stay (in days), severe complications, and subsequent surgical interventions. All pregnancies in which an early or late miscarriage was diagnosed will be identified via a database query. The analysis is based on clinical data from the respective study sites and represents a purely retrospective study. Data extraction at University Hospital Münster will be performed by Kathrin Oelmeier, while data from Florence Nightingale Hospital Düsseldorf will be collected by Ralf Schmitz. After anonymization, the combined datasets from both institutions will be analyzed and evaluated by Luisa Guter. The following clinical parameters will be recorded: maternal age, gestational age at diagnosis, gestational age at miscarriage, diagnosis of miscarriage, obstetric history, hemoglobin levels before and after miscarriage, administration of antibiotics, severe complications, relevant maternal comorbidities, fetal genetic causes, and duration of hospital stay.

—

Secondary

Measure	Time frame
Secondary endpoints were not defined.	—

Countries

Germany

Contacts

Public ContactRalf Schmitz

Florence-Nightingale Krankenhaus Düsselodorf

schmitzra@kaiserswerther-diakonie.de0211 409-2519

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026