Effectiveness and Safety of venovenous ECCO2R (extracorporeal carbon dioxide removal) using a renal replacement therapy device to facilitate lung-protective ventilation in patients with ARDS (acute respiratory distress syndrome) and AKI (acute kidney injury) treated at a tertiary pediatric intensive care unit

Effectiveness and Safety of venovenous ECCO2R (extracorporeal carbon dioxide removal) using a renal replacement therapy device to facilitate lung-protective ventilation in patients with ARDS (acute respiratory distress syndrome) and AKI (acute kidney injury) treated at a tertiary pediatric intensive care unit - vvECCO2R-CRRT children

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00038799

Enrollment

Registered

2026-04-23

Start date

2025-04-01

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric acute respiratory distress syndrome and acute kidney injury J80.0 N17.0

Interventions

Group 1: Retrospective analysis of all patients with PARDS (pediatric acute respiratory distress syndrome) and dialysis-dependent renal failure who received CO2 elimination (ECCO2R) via a renal replac

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: Pediatric ARDS and Indication for CRRT

Exclusion criteria

Exclusion criteria: not meeting inclusion criteria

Design outcomes

Primary

Measure	Time frame
Determination of ventilatory parameters as well as blood gas values and ventilation indices before and after initiation of ECCO2R-CRRT (before start; 1 h, 6 h, 12 h, 24 h, and 7 days after initiation of CO2 elimination).	—

Secondary

Measure	Time frame
Assessment of complications (bleeding, thrombosis, device failure) in the context of ECCO2R-CRRT.	—

Countries

Germany

Contacts

Public ContactHendryk Schneider

Klinik f. Allg. Kinder-und Jugendmedizin Freiburg

hendryk.schneider@uniklinik-freiburg.de076127043669

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Sep 10, 2026