Screening for hyponatremia, delirium, and anemia in cardiac surgery procedures E87.1 D62 F05
Conditions
Interventions
Group 1: Intervention group: After application of Brettschneider cardioplegia, patients receive hemofiltration with the DHF 02 hemofilter from LivaNova®.
Group 2: Control group: Patients receive stand
Sponsors
Universitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: - Surgery with cardioplegic Brettschneider solution - Patients who are capable of giving consent and are over 18 years of age - Elective cardiac bypass surgery with CPB - HB above 9 g/dl at the start of surgery
Exclusion criteria
Exclusion criteria: Exclusion criteria: - Refusal of study inclusion by the patient - Emergency surgery - Use of other cardioplegic solutions, such as Calafiore blood cardioplegia - Bicaval cannulation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate whether the use of the DHF 02 hemofilter from LivaNova® after application of Brettschneider cardioplegia leads to a more stable sodium concentration in the blood and less pronounced electrolyte shifts overall compared to treatment without hemofiltration. | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the frequency of electrolyte-related complications (e.g., hyponatremia, cardiac arrhythmias, and risk of delirium) between the study and control groups. To analyze whether hemofiltration contributes to improved clinical outcomes, e.g., through shorter stays in the intensive care unit due to delirium prophylaxis, reduced need for electrolyte replacement, or fewer cardiac arrhythmias. | — |
Countries
Germany
Contacts
Public ContactMarcin Zaradzki
Universitätsklinikum Heidelberg
Outcome results
None listed