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Pancreatic stone protein (PSP) for the early detection of sepsis in severe burns

Pancreatic stone protein (PSP) for the early detection of sepsis in severe burns

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038722
Enrollment
40
Registered
2025-12-11
Start date
2026-01-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns > 15 % total burned surface area T29.0

Interventions

Group 1: From routine morning blood draws on days 0–20, 50 µl are taken each time and analyzed using abioSCOPE. The quantitative result of the analysis (PSP) is usually displayed on the device's scree
that is, the test result is not visible but is stored on a patient-specific basis and only retrieved for evaluation after the test is completed. The PSP values ??are therefore not visible to the clini
only age and gender are documented for the analysis. This largely prevents the subsequent identification of patients. In accordance with legal requirements, the documentation forms are stored in the h

Sponsors

Klinikum St. Georg gGmbH
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients = 18 years Burns > 15% of total body surface area, 2nd-3rd degree

Exclusion criteria

Exclusion criteria: Lack of consent to study participation Hospital admission > 24 hours after burn injury Primarily palliative therapy Known acute or chronic pancreatitis or pancreatic cancer

Design outcomes

Primary

MeasureTime frame
Correlation between PSP and the clinical diagnosis of bacteremia and/or sepsis within the first 21 days after burn injury. PSP is determined bedside using AbioSCOPE on EDTA blood.

Secondary

MeasureTime frame
Sensitivity, specificity, and positive and negative predictive value of PSP compared to CRP, PCT, and IL6

Countries

Germany

Contacts

Public ContactJochen Gille

Klinikum St. Georg gGmbH

Jochen.Gille@sanktgeorg.de+49 341 9094706

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026