Joint Health Assessment in von Willebrand Disease

Joint Health Assessment in von Willebrand Disease - Joint_Health_VWD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00038694

Enrollment

Registered

2026-03-09

Start date

2026-07-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D68.00

Interventions

Group 1: Examination of joint status and functionality in patients with von Willebrand Disease (vWF activity < 30%): patients will be examined once by physical examination, determination of motility a

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: patients with confirmed hereditary von Willebrand Disease (VWF:RCo <30%

Exclusion criteria

Exclusion criteria: - patients with other causes for arthropathy or previous joint replacement surgery

Design outcomes

Primary

Measure	Time frame
Joint status/-functionality: -physical examination (Hemophilia Joint Health Score) -Motility test (nach Tinetti) -Hemo-FAST questionnaire (ärztlicher Teil) -joint sonography (HEAD-US Score)	—

Secondary

Measure	Time frame
patient questionnaires: - every day activites (Hemophilia Activity List, ACTIVLIM-Hemo, Hemo-FAST (patient part) - pain (Numeric rating scale) - health-related quality of life (ED-5Q) Furthers data collected from patient records: sex, age Type of Von Willebrand Disease and severity Von Willebrand and Factor VIII laboratory parameters Bleeding anamnesis (Annual bleeding rate, bleeding pattern, target joints) Therapy scheme Joint conditions(replacement/surgical interventions) Co-morbidities	—

Measure

Time frame

patient questionnaires: - every day activites (Hemophilia Activity List, ACTIVLIM-Hemo, Hemo-FAST (patient part) - pain (Numeric rating scale) - health-related quality of life (ED-5Q) Furthers data collected from patient records: sex, age Type of Von Willebrand Disease and severity Von Willebrand and Factor VIII laboratory parameters Bleeding anamnesis (Annual bleeding rate, bleeding pattern, target joints) Therapy scheme Joint conditions(replacement/surgical interventions) Co-morbidities

—

Countries

Germany

Contacts

Public ContactWolfgang Miesbach

Hämophiliezentrum/Hämostaseologie, Universitätsklinikum der Goethe Universität Frankfurt

Wolfgang.miesbach@unimedizin-ffm.de+496963015051

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026