Age-related changes in Biomechanics of Lower and upper Extremities

Age-related changes in Biomechanics of Lower and upper Extremities - ABLE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00038690

Enrollment

150

Registered

2025-12-09

Start date

2026-06-30

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M00-M99

Interventions

Group 1: The examinations/assessments involve the following steps: After receiving detailed written and verbal information and providing signed informed consent , demographic and anthropometric data (

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Group 1 (18–64): Independent walking; no relevant limb injury in the last 3 months. Group 2 (= 65): Independent walking and adequate balance; no relevant limb injury in the last 3 months.

Exclusion criteria

Exclusion criteria: Body weight >= 130 kg; Very sensitive skin (application of markers/sensors not possible); Neurological diseases (e.g., epilepsy, Parkinson's disease, cerebral palsy, stroke); Psychiatric disorder with limited capacity to consent/participate; Acute injury/illness causing limited mobility or a safety risk.

Design outcomes

Primary

Measure	Time frame
The examinations/assessments include: -Kinematic and Spatiotemporal Parameters (e.g., joint angles, ROM of hip/knee/ankle, stride length, cadence) via a Motion Capture System. -Kinetic Parameters (e.g., ground reaction forces) via treadmill-integrated force plates, and joint moments estimated through validated musculoskeletal models -Pressure-related Parameters (total, forefoot, and hindfoot pressures) via pressure-sensitive insoles. -Muscle Activation via Surface Electromyography (sEMG) sensors. -Patient-Reported Characteristics on physical activity via the International Physical Activity Questionnaire (IPAQ), as well as demographic metadata (age, sex, weight) via questionnaire.	—

Measure

Time frame

The examinations/assessments include: -Kinematic and Spatiotemporal Parameters (e.g., joint angles, ROM of hip/knee/ankle, stride length, cadence) via a Motion Capture System. -Kinetic Parameters (e.g., ground reaction forces) via treadmill-integrated force plates, and joint moments estimated through validated musculoskeletal models -Pressure-related Parameters (total, forefoot, and hindfoot pressures) via pressure-sensitive insoles. -Muscle Activation via Surface Electromyography (sEMG) sensors. -Patient-Reported Characteristics on physical activity via the International Physical Activity Questionnaire (IPAQ), as well as demographic metadata (age, sex, weight) via questionnaire.

—

Secondary

Measure	Time frame
Digital Biomarkers (e.g., for musculoskeletal loading, gait stability, and movement efficiency) are calculated/derived from the acquired sensor signals. Signal-Derived Features (e.g., acceleration, statistical descriptors such as mean and standard deviation) are calculated from the raw sensor data. Patient-Reported Characteristics on perceived movement ability, balance, stability, and activity are collected via questionnaire. Metadata (e.g., age, sex, height, weight) are collected via questionnaire.	—

Measure

Time frame

Digital Biomarkers (e.g., for musculoskeletal loading, gait stability, and movement efficiency) are calculated/derived from the acquired sensor signals. Signal-Derived Features (e.g., acceleration, statistical descriptors such as mean and standard deviation) are calculated from the raw sensor data. Patient-Reported Characteristics on perceived movement ability, balance, stability, and activity are collected via questionnaire. Metadata (e.g., age, sex, height, weight) are collected via questionnaire.

—

Countries

Germany, Luxembourg

Contacts

Public ContactStefan Ecker

Fraunhofer-Einrichtung für Individualisierte und Zellbasierte Medizintechnik IMTE

stefan.ecker@imte.fraunhofer.de+49451384448206

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026