Study evaluating various parameters in the blood and tissue of patients with endocrine orbitopathy in Graves' disease. An approach to personalized medicine.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00038656

Enrollment

300

Registered

2025-12-05

Start date

2025-06-06

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E05.0 H06.3 - Graves' disease with endocrine orbitopathy E05.0 H06.3

Interventions

Group 1: Arm 1: Graves' disease patients with varying degrees of endocrine orbitopathy are surveyed using the following questionnaires: • Specific questionnaire on quality of life for patients with Gr

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 18 with Graves' disease, both with and without endocrine orbitopathy of varying severity.

Exclusion criteria

Exclusion criteria: under the age of 18

Design outcomes

Primary

Measure	Time frame
Examination of the tissue and blood samples taken from patients as required Special attention should be paid to satisfaction with appearance in the long term after completion of all operations (decompression, strabismus, eyelids). This should be determined using the following questionnaires • EUGOGO • FACE Q • Specific questionnaire on the operation (explicitly designed for orbital decompression patients) • Quality of life (general questionnaire from the WHO)	—

Measure

Time frame

Examination of the tissue and blood samples taken from patients as required Special attention should be paid to satisfaction with appearance in the long term after completion of all operations (decompression, strabismus, eyelids). This should be determined using the following questionnaires • EUGOGO • FACE Q • Specific questionnaire on the operation (explicitly designed for orbital decompression patients) • Quality of life (general questionnaire from the WHO)

—

Countries

Germany

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026