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PANDA-study: Placement of Arterial and venous catheters in preterm Neonates in the first DAys after birth

PANDA-study: Placement of Arterial and venous catheters in preterm Neonates in the first DAys after birth

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038603
Enrollment
40
Registered
2026-02-17
Start date
2026-02-19
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

P07

Interventions

Group 1: Observational study. Video recording of very preterm infants during intravascular catheter placement and synchronized documentation of vital signs and ventilator settings.

Sponsors

LMU Klinikum
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Chronological age =7 days after birth - Clinical decision for an intravenous or intraarterial catheter - Infants cared for at the LMU hospital at the time of intervention

Exclusion criteria

Exclusion criteria: - Arterial or venous malformations - Inability of the parents to understand the study procedures due to cognitive or linguistic reasons - Declined parental consent

Design outcomes

Primary

MeasureTime frame
Changes in the oxygen saturation index, i.e. (MAP * FiO2 * 100) / SpO2 at pre-specified timepoints over the duration of the procedure Data will be collected by analyzing the video recording of vital parameters and ventilation parameters at the following timepoints Timepoints of data collection for PVC (peripheral venous catheter): - Baseline: prior to first handling of the infant - 20 seconds after first handling of the infant - 10 seconds before the end of the first handling of the infant - First disinfection of insertion site - Needle insertion - 10 seconds after needle insertion - If successful: Beginning and end of catheter fixation - If successful: 5 minutes after the end of the procedure including subsequent nursing care Timepoints of data collection for PICC-line (peripherally-inserted central catheter), UAC (umbilical arterial catheter) and UVC (umbilical venous catheter) : - Baseline: prior to first handling of the infant - 20 seconds after first handling of the infant - First disinfection of insertion site - Application of sterile drapes - Needle prick (only for PICC line) - Beginning of insertion of catheter (PICC-line/UAC/UVC) - End of insertion (PICC-line/UAC/UVC) - If successful: Beginning and end of catheter fixation

Secondary

MeasureTime frame
- Physiological outcomes at prespecified timepoints: vital signs, i.e. SpO2, HR, RR, pressure levels, tidal volumes, FiO2 - Maximum and minimum values of the respective vital signs, i.e. SpO2, HR, RR, pressure levels, tidal volumes, FiO2 during the entire procedure - Duration of catheter insertion - Effect of potential covariates (e.g. type of access, experience of the operator, site of insertion, use of visualization device, number of attempts)

Countries

Germany

Contacts

Public ContactVincent Gaertner

LMU Klinikum

vincent.gaertner@med.lmu.de+49 89 4400 57783

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026