HIDRA – Study on the prediction of intraoperative hypotension in women undergoing spinal anesthesia during cesarean section using perfusion index, pulse transit time, RR interval, and changes in pulse wave morphology

HIDRA – Study on the prediction of intraoperative hypotension in women undergoing spinal anesthesia during cesarean section using perfusion index, pulse transit time, RR interval, and changes in pulse wave morphology - HIDRA

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00038592

Enrollment

100

Registered

2026-01-15

Start date

2026-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative Hypotension

Interventions

Group 1: Women undergoing elective C-Section under spinal anesthesia. Analysis of routine perioperative vital signs with empahsis on Perfusion Index, RR-Interval, and PPG Pulse Wave morphology.

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: The inclusion criteria for this study are as follows: Adult women aged 18 years or older who are undergoing a cesarean section under primary spinal anesthesia for a duration of at least 30 minutes.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Cesarean section under general anesthesia, cesarean section with epidural catheter, congenital heart defects, atrial fibrillation or other arrhythmias, emergency cesarean section.

Design outcomes

Primary

Measure	Time frame
Primary endpoints: Sensitivity and specificity of the parameters perfusion index (PI), pulse transit time (PTT), RR interval, and pulse wave morphology (PWM) for detecting intraoperative hypotension (systolic blood pressure < 100 mmHg) during cesarean section under spinal anesthesia.	—

Secondary

Measure	Time frame
Secondary endpoints: Sensitivity and specificity for diastolic blood pressure 30%) in systolic, diastolic, and mean arterial pressure. Correlation of PTT with continuous blood pressure measurement and PWM with stroke volume estimation (ROC-AUC).	—

Countries

Germany

Contacts

Public ContactMichael Nordine

Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie

nordine@med.uni-frankfurt.de069 6301 84199

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026