Suspected acute myocardial infarction (AMI) within the spectrum of acute coronary syndrome without ST-segment elevation (NSTE-ACS). The study focuses on improving early, prehospital diagnosis and triage of these patients using a high-sensitivity troponin point-of-care test and a digital decision algorithm (ACS-Pathfinder).
Conditions
Interventions
Group 1: Patients with suspected non-ST-segment elevation acute coronary syndrome (NSTE-ACS) receive pre-hospital care according to local standards. In addition, a high-sensitivity rapid troponin tes
Sponsors
Leipzig Heart Science gGmbH
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: • Suspected myocardial infarction • Symptom onset >30 minutes before arrival of emergency medical services • Written consent
Exclusion criteria
Exclusion criteria: • STEMI detected on initial ECG • Unstable angina, hemodynamic instability, life-threatening arrhythmias, cardiac arrest • Non-ischemic causes requiring mandatory hospitalization • Emergency physician dispatch at the request of a primary care physician • Age <18 Jahre
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is hospital-confirmed myocardial infarction in patients enrolled in the PREDICT calibration study by emergency medical services with suspected ACS. | — |
Secondary
| Measure | Time frame |
|---|---|
| No formal endpoints; exploratory: recruitment, feasibility, acceptance, process evaluation. | — |
Countries
Germany
Contacts
Public ContactAngelica Avila Castillo
Leipzig Heart Science gGmbH
Outcome results
None listed