Skip to content

Retrospective analysis of pregnancy duration and perinatal outcomes in patients with threatening preterm birth under maintenance tocolysis versus acute tocolysis with Atosiban

Retrospective analysis of pregnancy duration and perinatal outcomes in patients with threatening preterm birth under maintenance tocolysis versus acute tocolysis with Atosiban

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038567
Enrollment
200
Registered
2025-12-15
Start date
2026-01-02
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

threatened preterm labour

Interventions

Group 1: Tocolysis for less or 48 hours Group 2: Tocolysis for longer than 48 hours

Sponsors

JKU Linz, Medizinische Fakultät
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: • All pregnant patients with threatened preterm birth between 22+ 0 and 33+ 6 weeks of gestation who received tocolysis/ACS and delivered at KUK • Therapy: Acute tocolysis with atosiban for a maximum of 48 hours during ACS administration or maintenance tocolysis with atosiban for >48 hours • Complete ACS administration (1st and 2nd dose)

Exclusion criteria

Exclusion criteria: • Premature births due to indications other than cervical insufficiency or premature labor (pre-eclampsia, bleeding, abnormal cardiotocography, amnionitis, umbilical cord prolapse, etc.) • Multiple pregnancies (Gemini) • PPROM (preterm premature rupture of membranes) • Restarting tocolysis if it has already been stopped

Design outcomes

Primary

MeasureTime frame
The aim of this exploratory study is a retrospective comparison of the duration of pregnancy between two groups with threatened preterm birth before the completed 34th week of gestation (34+0). Data collection will be done retrospectively from the hospital's internal system (KIS) and Viewpoint.The two groups are divided based on the duration of the tocolysis administered.

Secondary

MeasureTime frame
perinatal Outcome

Countries

Austria

Contacts

Public ContactSabine Enengl

JKU Linz, Medizinische Fakultät

sabine.enengl@kepleruniklinikum.at+43576808423722

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026