AVA: an AI-based tool to enhance vaccination readiness in primary care patients above 60 years of age with mild cognitive impairment

AVA: an AI-based tool to enhance vaccination readiness in primary care patients above 60 years of age with mild cognitive impairment - AVA (AI-supported Vaccination Assistant)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038562

Enrollment

305

Registered

2025-12-03

Start date

2026-08-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F06.7

Interventions

Group 1: Patients above 60 years of age with mild cognitive impairment (MCI) receive an automated telephone call from a voice assistant (AVA) controlled by artificial intelligence (AI). The patients a

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: - Mild cognitive impairment (MoCA® Blind Score 13-18 points) - Age: 60 years and older - Sufficient German language skills -Ability to independently answer and make telephone calls - Written informed consent

Exclusion criteria

Exclusion criteria: - clinical diagnosis of dementia (according to ICD-10) - hearing or communication impairment - previous illness that could jeopardise safe participation in the intervention (e.g. severe cardiovascular disease, severe depression) - serious mobility impairment - life expectancy < 6 months

Design outcomes

Primary

Measure	Time frame
Effectiveness of AVA on vaccination readiness against seasonal influenza in mild cognitively impaired patients aged 60 and older six weeks after the intervention; data sources are paper-based patient questionnaires.	—

Secondary

Measure	Time frame
- Change of vaccination rates against seasonal influenza and COVID-19 in comparison to the previous influenza vaccination season (2025/2026). The data sources are electronic health records at T0 (patient enrollment) and T1 (follow-up 1 six months after the intervention). - Mental Health: Symptoms of depression (PHQ-9) and generalized anxiety disorder (GAD-7); absolute change from T0 to T1. The data sources are paper-based patient questionnaires. - Patient Activation and Self-Management (PAM-13); absolute change from T0 to T1. The data sources are paper-based patient questionnaires. - Patient Assessment of Chronic Illness Care (PACIC): patient-centered measurement of the implementation of the Chronic Care Model (CCM); absolute change from T0 to T1. The data sources are paper-based patient questionnaires. -Patients’ perceptions of the physician-patient relationship were assessed by the Patient Reactions Assessment (PRA); absolute change from T0 to T1. The data sources are paper-based patient questionnaires.	—

Measure

Time frame

- Change of vaccination rates against seasonal influenza and COVID-19 in comparison to the previous influenza vaccination season (2025/2026). The data sources are electronic health records at T0 (patient enrollment) and T1 (follow-up 1 six months after the intervention). - Mental Health: Symptoms of depression (PHQ-9) and generalized anxiety disorder (GAD-7); absolute change from T0 to T1. The data sources are paper-based patient questionnaires. - Patient Activation and Self-Management (PAM-13); absolute change from T0 to T1. The data sources are paper-based patient questionnaires. - Patient Assessment of Chronic Illness Care (PACIC): patient-centered measurement of the implementation of the Chronic Care Model (CCM); absolute change from T0 to T1. The data sources are paper-based patient questionnaires. -Patients’ perceptions of the physician-patient relationship were assessed by the Patient Reactions Assessment (PRA); absolute change from T0 to T1. The data sources are paper-based patient questionnaires.

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Countries

Germany

Contacts

Public ContactLinda Sanftenberg

Institut für Allgemeinmedizin

Linda.Sanftenberg@med.uni-muenchen.de+4989440053388

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026