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Consciousness diagnostics of subacute and chronic patients using pupillometry

Consciousness diagnostics of subacute and chronic patients using pupillometry

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00038540
Enrollment
80
Registered
2025-11-26
Start date
2025-11-27
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorders of Conscicousness

Interventions

Group 1: Healthy control group Intervention: The pupillary response is measured by presenting cognitive and emotional tasks. The cognitive tasks are presented to the participants in a randomized order

Sponsors

Therapiezentrum Burgau
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Good german language skills, date of brain injury at least 21 days ago, patients with a UWS, MCS, MCS+, or EMCS diagnosis based on the CRS-R scale and, if applicable, SECONDs scale, informed consent from the patient or authorized representative

Exclusion criteria

Exclusion criteria: Invasive mechanical ventilation, strong central sedation medication through long-acting sedatives/benzodiazepines/opioids, acute epileptic seizure, eye disease with surgery on both sides, patients in EMCS and with proven aphasia

Design outcomes

Primary

MeasureTime frame
State of consciousness at time of pupillometry assessment

Secondary

MeasureTime frame
State of consciousness at 6 months follow-up Reliability of pupillometry

Countries

Germany

Contacts

Public ContactAndreas Peter Bender

Therapiezentrum Burgau

a.bender@therapiezentrum-burgau.de+498222404100

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026