Influence of short high-intensity training and tea on extracellular inflammasome particles - pilot study

Influence of short high-intensity training and tea on extracellular inflammasome particles - pilot study - HITEA

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038505

Enrollment

100

Registered

2025-11-19

Start date

2025-11-20

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General inflammation

Interventions

Group 1: Physical exertion without tea consumption The test subjects perform a short, high-intensity muscular exercise consisting of squats, push-ups, and squat jumps. The exercise is performed until

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: none

Exclusion criteria

Exclusion criteria: • Contraindication against maximum exertion according to the recommendation of the German Society of Cardiology (H.-J. Trappe and H. Löllgen) • Lack of consent • Pregnancy

Design outcomes

Primary

Measure	Time frame
Concentration of circulating ASC specks in serum measured by flow cytometry immediately before exercise (T0), immediately after exercise (T1), and 24 hours after exercise (T2), once without and once after drinking tea (alant root).	—

Secondary

Measure	Time frame
Interleukin concentrations at the same time points (e.g., interleukin 1ß, interleukin 6, interleukin 18 measured by ELISA in serum) and muscle stress parameters (e.g., CK)	—

Countries

Germany

Contacts

Public ContactAlexander Kogel

Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig

Alexander.kogel@medizin.uni-leipzig.de+493419712650

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026