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Malignant, mature T-cell lymphomas – Retrospective analysis of epidemiology, outcomes, and treatment strategies at a university medical center with a focus on autologous and allogeneic stem cell transplantation

Malignant, mature T-cell lymphomas – Retrospective analysis of epidemiology, outcomes, and treatment strategies at a university medical center with a focus on autologous and allogeneic stem cell transplantation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038503
Enrollment
150
Registered
2025-12-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C84 C91.5 C91.6 C86

Interventions

Group 1: Patients aged > 18 years with a diagnosis of peripheral T-cell lymphoma (PTCL) (ICD-10 codes - C84.0-C84.9
C86.0-C86.6
C91.50 and C91.51
C91.60 and C91.61) registered from 01/2004 to 10/2025 at the University Hospital Essen.

Sponsors

Universitätsklinikum Essen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with aggressive mature T-NHL treated at university hospital Essen between 2004 to 2025

Exclusion criteria

Exclusion criteria: Age < 18 years Premature T-NHL, primary cutaneous or non-aggressive T-NHL

Design outcomes

Primary

MeasureTime frame
Analysis of Overall survival (OS) ans progression free survival (PFS) of the whole study population. Single time analysis at the end of data collection.

Secondary

MeasureTime frame
Comparison of OS and PFS in patients with an without stem cell therapy (autologous or allogenic). OS and non-relaps.mortylity (NRM) in the study population that received a stem cell transplantation in first or second treatment line.

Countries

Germany

Contacts

Public ContactKai Arne Plümer

Universitätsklinikum Essen

kaiarne.pluemer@uk-essen.de+4920172385539

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026