Role of expectation in open-label placebos

Role of expectation in open-label placebos - OLPext

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038490

Enrollment

105

Registered

2025-11-26

Start date

2025-12-01

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychological well-being

Interventions

Group 1: Open-label placebos with information (placebos for five days, two each day) Group 2: Open-label placebos without information (placebos for five days, two each day) Group 3: Control group (no

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: No

Exclusion criteria

Exclusion criteria: Known psychiatric or neurological diseases

Design outcomes

Primary

Measure	Time frame
Primary outcome measure is negative emotionality, measured using the DASS-21 (Depression, Anxiety, and Stress Scales). The questionnaire is completed at the beginning and end of the study.	—

Secondary

Measure	Time frame
Secondary outcome measure is mood measured using the PSQI (Pittsburgh Sleep Quality Index). The questionnaire is completed at the beginning and end of the study.	—

Countries

Germany

Contacts

Public ContactMichael Schaefer

Medical School Berlin

michael.schaefer@medicalschool.berlin.de+49 (30) 76683753

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026