I27
Conditions
Interventions
Group 1: - Examination of the microcirculation and the sublingual perfused boundary region using videomicroscopy (Glycocalyx Measurement Software™, GlycoCheck BV, Netherlands):
The assessment of the v
Sponsors
Klinikum der Universität München, Abteilung für Kinderkardiologie und pädiatrische Intensivmedizin
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Diagnosted pulmonary hypertension via right heart catheter -mPAP measured >20 mmHg Given written Consent, for minors at least one parent or legal guardian has to give written consent
Exclusion criteria
Exclusion criteria: No written consent Acute infection at time of examination Underlying oncological or neuromuscular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thickness of sublingual endothelial glycocalyx measured using Glycocalyx Measurement Software™, GlycoCheck BV, Netherlands - inital examinatiom either while control appointment at the clinic or while hospital stay for right heart catheter - follow up examination 3-6 months After first examimation during control appointment | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes comprised microvascular variables derived from the same recordings as PBR measurement : functional capillary density, capillary blood volume (CBV, microvascular blood flow and erythrocyte velocity (µm/s) | — |
Countries
Germany
Contacts
Public ContactJoseph Pattathu
Klinikum der Universität München, Abteilung für Kinderkardiologie und pädiatrische Intensivmedizin
Outcome results
None listed