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Relationship and Depression Dynamics in Treatment: A randomized-controlled trial of individual versus couple-enhanced behavioral activation

Relationship and Depression Dynamics in Treatment: A randomized-controlled trial of individual versus couple-enhanced behavioral activation - READDY

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00038464
Enrollment
100
Registered
2025-11-19
Start date
2025-11-24
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32 F33

Interventions

Group 1: This group will receive 4-6 individual probationary sessions that focus on diagnostic and functional assessment as well as case formulation (following standard procedure for psychotherapy in

Sponsors

Philipps-Universität Marburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: a. Patient must be accepted for treatment at the outpatient clinic Marburg b. Patient with primary diagnosis of Major Depressive Disorder according to DSM-5 criteria und BDI-II score >= 20 c. Currently in a committed relationship for at least 6 months d. Living together or regular contact (some contact on at least 5 days/week) e. Patients and partners willing to participate f. Partners and patients willing and able to attend joint sessions if assigned to CE-BA g. Both partners have sufficient German language skills in order to participate in the assessments and in treatment h. Patients have to have public health insurance i. Patients have consented to their participation in the Z-Project in DYNAMIC

Exclusion criteria

Exclusion criteria: a. High risk of harm to self or others b. Intimate partner violence or threat of violence in the past year c. Currently undergoing couple therapy or couples counseling d. Anticipated changes of psychiatric medication during active treatment e. Any psychosis or schizophrenia, unless stably remitted on maintenance therapy for at least 1 year f. Developmental disability that would impair the ability to benefit from the intervention

Design outcomes

Primary

MeasureTime frame
Change in self-rated depression severity (BDI-II) - patients. Assessed with the Beck’s Depression Inventory II (BDI-II) at baseline, mid-, post-treatment, and at both follow-up measurement time-points (6-month and 12-month after the end of treatment).

Secondary

MeasureTime frame
2. Change in clinician-rated depression severity (HAMD) - patients Assessed with the 21-item version of the Hamilton Depression (HAMD) at baseline, post-treatment, and both follow-up measurement time-points (6- and 12-month after the end of treatment). 3. Change in self-rated depression severity (BDI-II) - partners Assessed with the Beck’s Depression Inventory II (BDI-II) at baseline, mid-, post-treatment, and at both follow-up measurement time-points (6-month and 12-month after the end of treatment). 4. Change in self-rated activation levels (BADS-SF) - patients and partners Assessed with the German 9-item Behavioral Activation for Depression Scale short form (BADS-SF) at baseline, mid-, post-treatment, and at both follow-up measurement time-points (6- and 12-month after the end of treatment). 5. Change in self-rated relationship satisfaction (CSI-16) - patients and partners Assessed with the German 16-item version of the Couple Satisfaction Inventory (CSI-16) at baseline, mid, post-treatment, and at both follow-up measurement time-points (6- and 12-month after the end of treatment). 6. Change in self-rated affective communication and problem solving (MSI-R) - patients and partners Assessed with the German 32-item Marital Satisfaction Index (MSI-R) at baseline, post-treatment, and at both follow measurements time-points (6- and 12-month after the end of treatment). 7. Change in self-rated life satisfaction (SWLS) - patients and partners Assessed with the German 5-item Satisfaction of Life Scale (SWLS) at baseline, post-treatment, and at both follow-up measurement time-points (6- and 12-month after the end of treatment). 8. Change in self-rated expressed emotion (FQ) - partners Assessed with the German 20-item Family Questionnaire (FQ) at baseline, pre-, mid-, post-treatment, and both follow-up measurement time-points (6- and 12-month after the end of treatment). Other Pre-specified Outcomes 9. Change in self-rated Dyadic Coping (DCI) - pati

Countries

Germany

Contacts

Public ContactMelanie S. Fischer

Philipps-Universität Marburg

melanie.fischer@uni-marburg.de+49 6421 28-23731

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026