VR-supported intervention for stress reduction in patients undergoing early neurological rehabilitation (Phase B)

VR-supported intervention for stress reduction in patients undergoing early neurological rehabilitation (Phase B) - FOREST

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038456

Enrollment

Registered

2025-12-03

Start date

2025-10-13

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurological patients right after a neurological event (e.g. stroke)

Interventions

Group 1: The active condition consists of three sessions of virtual forest bathing (3D, 360°) delivered via a head-mounted display (HMD) for 14 minutes each. The immersive forest environment is comple

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Patients in neurological early rehabilitation (phase B)

Exclusion criteria

Exclusion criteria: - Contra indications (e.g. F05, Delir)

Design outcomes

Primary

Measure	Time frame
In a crossover design, neurological patients with mobility impairments who are undergoing early rehabilitation (Phase B) complete three sessions of a virtual forest-bathing intervention and one control intervention. The timing of the control condition (Day 2, 3, or 4) is randomly assigned. The primary outcome is the pre-post change in state anxiety (State subscale of the State–Trait Anxiety Inventory; STAI; Grimm, 2009) during the VR intervention on the last day of intervention compared to the pre–post change during the control intervention.	—

Measure

Time frame

In a crossover design, neurological patients with mobility impairments who are undergoing early rehabilitation (Phase B) complete three sessions of a virtual forest-bathing intervention and one control intervention. The timing of the control condition (Day 2, 3, or 4) is randomly assigned. The primary outcome is the pre-post change in state anxiety (State subscale of the State–Trait Anxiety Inventory; STAI; Grimm, 2009) during the VR intervention on the last day of intervention compared to the pre–post change during the control intervention.

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Secondary

Measure	Time frame
- Positive and Negative Affect (Positive and Negative Affect Schedule, PANAS; Breyer & Bluemke, 2016) - Perceived stress - pre and post (Numeric Rating Scale, NRS) - Perceived restoration - pre and post (Numeric Rating Scale, NRS) - Simulator Sickness - post (Simulator Sickness Questionnaire, SSQ; Kennedy et al., 1993) - Heart rate/heart rate variability - Skin conductance level - Experience with VR (before the study) - Personal attitude towards VR Forest Bathing (before and after the intervention)	—

Measure

Time frame

- Positive and Negative Affect (Positive and Negative Affect Schedule, PANAS; Breyer & Bluemke, 2016) - Perceived stress - pre and post (Numeric Rating Scale, NRS) - Perceived restoration - pre and post (Numeric Rating Scale, NRS) - Simulator Sickness - post (Simulator Sickness Questionnaire, SSQ; Kennedy et al., 1993) - Heart rate/heart rate variability - Skin conductance level - Experience with VR (before the study) - Personal attitude towards VR Forest Bathing (before and after the intervention)

—

Countries

Germany

Contacts

Public ContactPhilipp Keune

Klinikum Bayreuth GmbH Klinik Hohe Warte

philipp.keune@klinikum-bayreuth.de0921 400-753461

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026