Sleep restriction
Conditions
Interventions
Group 1: Sleep restriction condition: Participants reduce their habitual sleep duration by 2 hours for 5 consecutive nights. Their sleep and rest-activity rhythms will be recorded at home via an EEG h
Sponsors
LMU München
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: regular sleep-wake rhythm normal weight German-native speaker or comparable language skills non-smoker
Exclusion criteria
Exclusion criteria: acute or chronic illnesses, including sleep disorders acute or chronic medication use (except for monophasic oral contraceptives in women) alcohol or drug dependence shift work in the last 6 weeks travel across different time zones in the last 6 weeks blood or plasma donation in the last 4 weeks participation in studies involving medication in the last 2 months pregnancy and breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Concentration of inflammation-related parameters in blood (incl. differential blood count, C-reactive protein, interleukin-6, klotho) before and after the experimental conditions - Performance in neurocognitive tests (incl. vigilance, short- and long-term memory, executive functions) performed at the end of each experimental condition | — |
Secondary
| Measure | Time frame |
|---|---|
| - sleep architecture, sleepiness - sleep-associated and immune-modulatory hormones (growth hormone, prolactin, cortisol) | — |
Countries
Germany
Contacts
Public ContactLuciana Besedovsky
LMU München
Outcome results
None listed