Change in exercise-induced oxidative and inflammatory stress response, as well as the number of days with upper respiratory tract infections.
Conditions
Interventions
Group 1: Name: Intervention group – Zell Oxygen® Immunkomplex
Description:
Daily intake of one portion of Zell Oxygen® Immunkomplex (1 dose in 250 ml liquid with breakfast) for 8 weeks.
Two acute test
Sponsors
Universität Wien
Eligibility
Sex/Gender
Male
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Male sex Age between 18 and 40 years Stable body weight and dietary habits No subjective symptoms during physical exertion No regular extensive resistance or endurance training (less than 3 hours per week) No contraindications to nutritional supplementation or ergogenic aids
Exclusion criteria
Exclusion criteria: Smoking (> 5 cigarettes per week) Cachectic or consumptive diseases within the past 5 years Known serious internal diseases with corresponding laboratory abnormalities (transaminases > 2 × upper normal limit, creatinine > 1.3 mg/dl) Contraindications to physical exercise (e.g. chronic heart disease, arrhythmia, valvular disease, liver or kidney disease, arthritis; general exclusion criteria according to ACSM 2009) Chronic inflammatory diseases or immune deficiencies Presence of insulin-dependent diabetes mellitus (IDDM) Contraindications to performing a bioelectrical impedance analysis (e.g. cardiac pacemaker, functional prosthesis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Beginning and after 12 weeks: Change in whole-blood ROS (Reactive Oxygen Substances) concentration (EPR spectroscopy) | — |
Secondary
| Measure | Time frame |
|---|---|
| Beginning and after 12 weeks: IL-6, TNF-a, hs-CRP, FRAP, MDA, glutathione, SOD, catalase, GSHPX, oxidative DNA damage, phase angle and body composition by BIA. Numbers of upper respiratory tract infections (URTI) | — |
Countries
Austria
Contacts
Public ContactDaniel König
Universität Wien
Outcome results
None listed