Algorithm-Guided Intraoperative Propofol Prediction in Target-Controlled Infusion: A Prospective Randomised Study for Personalised Waste Reduction

Algorithm-Guided Intraoperative Propofol Prediction in Target-Controlled Infusion: A Prospective Randomised Study for Personalised Waste Reduction - Predict

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038338

Enrollment

400

Registered

2026-06-05

Start date

2026-07-01

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Propofol wastage

Interventions

Group 1: Intraoperative propofol consumption prediction for remaining duration of surgery Group 2: No prediction (control)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Qualified medical staff specialising in anaesthesiology (junior doctors, specialist doctors, senior doctors) - Operating theatre support for total intravenous anaesthesia

Exclusion criteria

Exclusion criteria: • Rejection

Design outcomes

Primary

Measure	Time frame
What: Propofol Waste (mg/procedure) When: Post OP How: Via questionnaire	—

Secondary

Measure	Time frame
- Syringe changes (/procedure) - Estimated Duration error (Duration predicted by surgeon/actual duration) - Depth of anaesthesia (mean BIS) - Vital parameters (spO2 and RR differential during induction) - Used Propofol (mg/kg BW/h)	—

Countries

Germany

Contacts

Public ContactFlorian Windler

Universitätsklinikum Bonn

florian.windler@ukbonn.de022828719407

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026