New method for determining the optimal PEEP in mechanically ventilated ARDS patients.

New method for determining the optimal PEEP in mechanically ventilated ARDS patients. - Stenquist optPEEP

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038310

Enrollment

Registered

2025-10-30

Start date

2025-12-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS

Interventions

Group 1: PEEP determination: 1.According to the new PEEP step method 2.According to esophageal pressure measurement Group 2: PEEP determination: 1.According to esophageal pressure measurement 2.Accord

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Mechanical ventilation and ALI/ARDS

Exclusion criteria

Exclusion criteria: Age 50) Pregnant patients Patients with massive pulmonary edema Use during electricity-based therapies such as electrosurgery or electrocoagulation Use in the presence of strong magnetic fields or in combination with other bioimpedance methods Contraindications to esophageal catheter: injuries/pathologic conditions of the esophagus

Design outcomes

Primary

Measure	Time frame
Agreement of transpulmonary pressures between the new PEEP-step method and esophageal pressure measurement.	—

Secondary

Measure	Time frame
Changes in oxygenation and decarboxylation, as well as in the regional ventilation distribution, after PEEP settings according to the new PEEP step method, according to esophageal pressure measurement, according to ARDSnet, and according to EIT	—

Countries

Germany

Contacts

Public ContactOnnen Mörer

Universitätsmedizin Göttingen Klinik für Anästhesiologie

Onnen.Moerer@med.uni-goettingen.de0551 39 67740

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026