D68.8
Conditions
Interventions
Group 1: Cardiac surgery patients undergoing minimally invasive aortic valve replacement in whom intraoperative rotational thromboelastometry (ROTEM) was performed during cardiopulmonary bypass or sho
Sponsors
Herzzentrum Dresden Universitätsklinik
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients who have undergone elective minimally invasive aortic valve replacement between 1 Jul 2022 and 31 Oct 2025 are included.
Exclusion criteria
Exclusion criteria: Patients who did not discontinue preoperative medication affecting blood coagulation in a timely manner (DOAC > 48 hours, ADP receptor antagonists 5 days) are excluded. Patients with congenital coagulation disorders, thrombocytopenia, and end-stage renal failure are also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and volume of transfused red blood cell concentrates and therapeutic plasma. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of anticoagulants Hemostasis time Postoperative blood loss in the first 6, 12, and 24 hours Reoperation rate for bleeding in the first 24 hours Transfusion-free time Incidence of acute renal failure Incidence of thromboembolic complications Length of stay in the intensive care unit Intrahospital mortality | — |
Countries
Germany
Contacts
Public ContactJens Fassl
Herzzentrum Dresden Universitätsklinik
Outcome results
None listed