Evaluation of antimicrobial photodynamic therapy (aPDT) as adjunctive therapy in patients undergoing supportive periodontal therapy

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038282

Enrollment

Registered

2025-10-30

Start date

2025-10-27

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontitis K05.2 K05.3

Interventions

Group 1: control group (without aPDT): Follow-up examinations (periodontal status, measurement of aMMP-8) with supra- and subgingival cleaning (mechanical only) Examinations at baseline, after 3, 6, a

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: at least 6 months in the UPT program At least one tooth with ST>= 4 mm in each quadrant No systemic contraindications or serious illnesses

Exclusion criteria

Exclusion criteria: Pregnant and breastfeeding women Severe systemic diseases (e.g., uncontrolled diabetes, asthma, endocarditis prophylaxis necessary) Severe dry mouth or other oral diseases Previous periodontal surgery or previous use of aPDT Lack of cooperation Medications that could interfere with the success of therapy (antibiotics, immunomodulators)

Design outcomes

Primary

Measure	Time frame
Probing pocket dephth (PPD) after 3, 6 and 12 months	—

Secondary

Measure	Time frame
plaque index, gingival recessions, BOP, mobility, furcation involvement	—

Countries

Germany

Contacts

Public ContactNicole Arweiler

Klinik für Parodontologie und peri-implantäre Erkrankungen

arweiler@med.uni-marburg.de+49 6421 58 63235

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026