Quantification of the Keyhole Concept in Cranial Neurosurgery: A Pilot Study on Personalized Craniotomy Planning

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00038273

Enrollment

Registered

2025-12-09

Start date

2026-04-15

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C71 D33

Interventions

Group 1: Intervention group: First phase: The imaging data (CT and MRI from a single time point each) from approximately 20 patients with intracranial tumors will be used to generated 3D-printed model

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients undergoing elective surgery for a brain tumor Ability to provide informed consent

Exclusion criteria

Exclusion criteria: Re-do craniotomies Presence of multiple intracranial tumors Patients without the ability to provide informed consent

Design outcomes

Primary

Measure	Time frame
Primary quantitative endpoint: deviation in diameter between the preoperatively calculated craniotomy and the intraoperatively required bone opening. Primary qualitative endpoint: scores ranging from 1 to 3 for both the quality of surgical handling (maneuverability) and the adequacy of exposure provided by the modelled approach.	—

Secondary

Measure	Time frame
Gross total tumor resection Operative parameters (operating time, blood loss, intraoperative complications)	—

Countries

Switzerland

Contacts

Public ContactJonathan Rychen

Universitätsspital Basel, Klinik für Neurochirurgie

jonathan.rychen@usb.ch+41 61 55 65117

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026