Outcomes of hormonal treatment for transgender patients: comparison of treatment beginning in youth versus adulthood.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00038242

Enrollment

200

Registered

2025-10-27

Start date

2025-03-06

Completion date

Unknown

Last updated

2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F64.0

Interventions

Group 1: Questionnaires and when consent is given additionally already collected laboratory and clinical data

Eligibility

Sex/Gender

All

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: - Diagnosis F64.0 (Transsexualism) according to ICD-10 - Start of treatment with GnRHa or GAH at least one year prior and not before 1st January 2015

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
- Efficacy of hormonal treatment of minors with gender dysphoria - cross-sectional capture at time of survey - defined by questionnaires WHO-5, RSES, PHQ-9 and TCS	—

Secondary

Measure	Time frame
- Safety of early treatment concerning higher incidence of detransitions - cross-sectional capture at time of survey - defined by detransition score 0 - 9 (integer)	—

Countries

Germany

Contacts

Public ContactClemens Kamrath

Universitätsklinikum Freiburg Klinik für Allgemeine Kinder- und Jugendmedizin

clemens.kamrath@uniklinik-freiburg.de+49 761 270 96 44140

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026