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NeuroDance – Ameliorating the symptoms and promoting the well-being in patients with Parkinson's Disease (PD) and related disorders

NeuroDance – Ameliorating the symptoms and promoting the well-being in patients with Parkinson's Disease (PD) and related disorders - NeuroDance

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00038241
Enrollment
520
Registered
2026-03-10
Start date
2025-06-30
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Morbus Parkinson’s syndrome (stages 1–4 according to Hoehn & Yahr) G20

Interventions

Group 1: Intervention group: Attendance in a dance intervention. (2 weekly sessions of 60 minutes over 18 weeks) Group 2: Passive control group: no attendance in a dance intervention (no intervention)

Sponsors

Znanstveno-raziskovalno središce Koper (ZRS Koper)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosed Parkinson’s disease (Hoehn and Yahr stages 1 to 4) Comprehension of verbal and action-related instructions.

Exclusion criteria

Exclusion criteria: Diagnosed Parkinson’s disease, Hoehn and Yahr stage 5 Severe cognitive impairment (MoCA = 21 points)

Design outcomes

Primary

MeasureTime frame
Functional mobility in individuals with Parkinson’s disease, defined as a composite of gait ability, balance, strength, and motor control, was assessed at two measurement time points—before the start (pre-test) and after completion (post-test) of the 18-week dance intervention. Assessment is conducted using the following standardized test battery: - 10-Meter Walking Test (10MWT): Evaluation of gait speed and stability. -Timed-Up-and-Go (TUG) in standard, manual, and cognitive versions to assess complex mobility and dual-task performance. -Five Times Sit-to-Stand Test (FTSTS): Measurement of lower-limb strength and functional transfer ability. -Four-Square Step Test (FSST) and 360° Turn Test (360°TT): Evaluation of dynamic balance and coordination. -Limits of Stability (LOS) and Sensory Organization Test (SOT): Analysis of static and dynamic balance using the Balance Master system. -Handgrip Strength (Dynamometry): Measurement of isometric muscular force as a physiological marker. Additionally, spatiotemporal gait parameters (stride length, cadence, and gait cycle duration) were recorded using the OptoGait and NORAXON system. Examination of neurophysiological adaptations: Changes in cortical activation and cortico-muscular coupling, assessed at pre- and post-intervention. -Spectral EEG analysis: Evaluation of activation patterns in motor-relevant cortical networks. -EEG-EMG coherence analysis: Quantification of functional coupling between cortical and muscular activity using an EEG-system by BrainProducts. These test and measurement procedures provide the basis for evaluating motor improvements resulting from the dance intervention through pre-post comparisons.

Secondary

MeasureTime frame
1. Fear of Falling: Perceived fear of falling in daily and social situations, assessed at both pre- and post-intervention time points. Data are collected using the Falls Efficacy Scale – International (FES-I) (16 items, four-point Likert scale). The instrument quantifies the degree of fall-related concern across a range of physically and socially demanding situations.? 2. Quality of Life: Health-related and general perceived quality of life are assessed at pre- and post-intervention using the Parkinson’s Disease Questionnaire (PDQ-39), and at pre-intervention, week 5, week 9, and post-intervention using the WHO-5 Well-Being Index (WHO-5). Assessment procedures: PDQ-39: Captures eight domains of quality of life, including mobility, emotional stability, social support, and stigma (self-report, 39 items). WHO-5: Evaluates subjective well-being throughout the intervention period at short intervals for longitudinal monitoring.

Countries

Germany

Contacts

Public ContactManca Peskar

Znanstveno-raziskovalno središce Koper (ZRS Koper)

manca.peskar@zrs-kp.si+386 5 663 77 00

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Sep 18, 2026