D57.0
Conditions
Interventions
Group 1: Not interventional. Eligible patients with chronic hemolytic anemia or healthy volunteers will be asked whether they are willing to participate. After giving consent, patients will provide an
Sponsors
LMU Klinikum
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with hereditary anemias or healthy control group.
Exclusion criteria
Exclusion criteria: Any comorbidities or conditions that make the patient or healthy control not suitable for participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Registrating vitamin deficiencies in the patient group compared to the control group. After giving consent, patients will provide an additional blood sample—up to 30 ml—during a blood draw already scheduled for routine care. We will perform additional laboratory tests concerning vitamin status, amino acids and blood lipids. We will also ask the patient about lifestyle and diet and we will ask for measurable signs of disease activity, like anemia or crisis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Registration of the influence of vitamin deficiencies on the clinical course. A documentation of disease activity will be made. Therefore measurable signs of disease will be documented and compared, like Hemoglobin levels or pain crisis. | — |
Countries
Germany
Contacts
Public ContactLaura Distelmaier
LMU Klinikum
Outcome results
None listed