Investigation of possible factors that influence therapy adherence in HIV-positive people with a migration background
Conditions
Interventions
Group 1: This cross-sectional, population-based epidemiological observational cohort study aims to investigate barriers to ART adherence among miPLHIV compared to gPLHIV. Recruitment will occur over a
Sponsors
GILEAD Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: • HIV Status: Participants must have a documented HIV diagnosis and must either be currently receiving ART or have been previously prescribed ART but are not adherent to the regimen at time of recruitment. • ART Prescription: Participants must have been prescribed ART for at least six months prior to study recruitment • Nationality -- Participants with a migration background: Individuals whose citizenship at the time of their birth was not German or who have at least one parent not born with German citizenship --Native German participants: Individuals whose citizenship at the time of their birth was German and whose parents were also born with German nationality • Proficiency in one of the study languages (German, English, French, Turkish, Arabic, Russian or Ukrainian) • Participant able to provide informed consent, acknowledging their understanding of study purpose, procedures, and data collection process • Participant must be willing to complete online multi-lingual questionnaire
Exclusion criteria
Exclusion criteria: • Under 18 or over 65 years of age • Individuals who are not currently on ART or who had previous ART prescriptions but have not been prescribed ART for at least six months • Pregnancy or breastfeeding • Severe cognitive impairment • Individuals who cannot understand any of the available languages for the online multi-lingual questionnaire
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to identify the specific socioeconomic, cultural, psychological and healthcare related barriers to sustained ART adherence among miPLHIV compared to gPLHIV. The study will adopt a community-engaged approach, ensuring that feedback from PLHIV, including miPLHIV, is incorporated at all stages, from design to execution. This community involvement will guide the development of the survey questionnaire, ensuring that it accurately captures the lived experiences and challenges faced by PLHIV. Specifically, the study will: 1.Assess the impact of socioeconomic factors (e.g., income, employment, healthcare access) on ART adherence among both groups. 2.Investigate the role of cultural and psychological barriers (e.g., stigma, acculturation stress, cultural beliefs about HIV) in non-adherence. 3.Examine healthcare system barriers (e.g., language difficulties, lack of culturally competent care) affecting both groups, with a focus on miPLHIV-specific issues. 4.Formulate evidence-based recommendations for healthcare providers and policymakers to improve ART adherence, particularly for miPLHIV. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary endpoints of this study aim to complement the primary aim of identifying barriers to ART adherence by focusing on specific factors that could inform tailored interventions and strategies to improve adherence among miPLHIV. These objectives are outlined as follows: 1. Examine the role of social support in ART adherence: This objective will assess the impact of social networks, including family, peers, and community organizations, on ART adherence among miPLHIV and gPLHIV. It will investigate how social support influences adherence behaviors and identify potential gaps in social support for miPLHIV. 2. Evaluate the influence of healthcare provider relationships on ART adherence: This objective will explore how the quality of interactions between PLHIV and healthcare providers affects ART adherence. It will particularly focus on the role of cultural competence and communication barriers in the context of miPLHIV, with the aim to identify areas where healthcare providers can be better equipped to support adherence. 3. Analyze healthcare system barriers affecting ART adherence: This objective will investigate systemic barriers within the healthcare infrastructure, such as access to culturally competent care, availability of services, and the role of language difficulties. It will focus on identifying healthcare system factors that disproportionately affect miPLHIVs ability to adhere to ART. | — |
Countries
Germany
Contacts
Public ContactAnja Potthoff
Walk In Ruhr - Zentrum für Sexuelle Gesundheit und Medizin
Outcome results
None listed