Coronary Heart Disease (CHD) I25.1
Conditions
Interventions
Group 1: Inclusion required at least one intermediate non-culprit lesion (40-90% diameter stenosis) in a coronary artery with a reference diameter = 2.5 mm. vFFR and QFR were calculated in triplicate
Sponsors
Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Eligibility criteria included patients aged 18 years or older presenting with chronic coronary syndrome (CCS) or requiring staged assessment of non-culprit lesions following non-ST-elevation myocardial infarction (NSTEMI) or ST-elevation myocardial infarction (STEMI), as depicted in Figure 1. Inclusion required at least one intermediate non-culprit lesion (40-90% diameter stenosis) in a coronary artery with a reference diameter = 2.5 mm
Exclusion criteria
Exclusion criteria: Exclusion criteria included STEMI within 72 hours, cardiogenic shock, severe renal impairment (GFR = 30 mL/min/1.73 m²), left ventricular ejection fraction < 30%, ventricular arrhythmias, contrast agent- or adenosine intolerance, severe vessel tortuosity, lesion overlap, or inadequate image quality. Image quality criteria: 1. Bad contrast filling (n=2) 2. Vessel overlap (n=2) 3. Vessel foreshortening (n=5) 4. Missing projections 15fps (n=2) 5. Table movement (n=1) 6. Significant aortic stenosis (n=1) 7. Side branch analysis (n=2)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study therefore aimed to assess the diagnostic accuracy of vFFR and QFR against iFR and RFR. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inter- and intra-observer reliability of vFFR and QFR. | — |
Countries
Germany
Contacts
Public ContactKarsten Lenk
Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig
Outcome results
None listed