P27.1
Conditions
Interventions
Group 1: Former very low birth weight (VLBW) infants born before the completed 32nd week of gestation at the LMU hospital perinatal center at the age of 12 and 18 years will be examined at the ages of
Sponsors
LMU München
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: Former VLBW infants born before the completed 32nd week of gestation at the LMU hospital perinatal center as well as term born infants at the age of 12 years.
Exclusion criteria
Exclusion criteria: • No parental or caregivers´ consent. • Severe neurologic impairment that does not allow lung function and exercise capacity testing. • Severe congenital malformation according to the international classification (excluding inguinal hernia, PDA, atrial septal defects, ventricular septal defects and all congenital anomalies that do not affect pulmonary, cardiovascular and psychomotor capacities). • Oligohydramnios before 22 weeks´ gestation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary target variable according to which the evaluation is performed: BPD diagnosis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung function and cardiovascular phenotype in BPD as well as differences in microbial-epigenetic-immuno-metabolic profiling between infants with and without BPD. Further, the PRIORITY study covers former very preterm infants that are at particular risk for lifelong sequelae of psychomotor outcomes, somatic growth and subjective wellbeing, education and participation in the labor market and building up friendships and families. | — |
Countries
Germany
Contacts
Public ContactKai Martin Förster
LMU München
Outcome results
None listed