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Ginkgo biloba in post-COVID patients and ME/CFS patients with cognitive deficits and brain fog – a retrospective analysis of routine data from the University Outpatient Clinic for Naturopathic Treatment and Prevention

Ginkgo biloba in post-COVID patients and ME/CFS patients with cognitive deficits and brain fog – a retrospective analysis of routine data from the University Outpatient Clinic for Naturopathic Treatment and Prevention - Ginkgo brain-fog

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038151
Enrollment
35
Registered
2026-01-26
Start date
2026-01-19
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F06.7

Interventions

Group 1: Retrospective analysis of routine data from 1st of June 2023 and August 31, 2025

Sponsors

Charité-Universitätsmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Diagnoses of post-COVID syndrome (U09.9) or post-viral fatigue (G93.3) or myalgic encephalomyelitis/chronic fatigue syndrome (G93.3) 2. Presence of neurocognitive disorders (brain fog, memory, concentration, or word-finding difficulties) 3. Prescription of Ginkgo biloba at the first appointment 4. Age 18-65 years of any gender 5. Patients who attended their first and second appointments at the University Outpatient Clinic for Naturopathy and Prevention between June 1, 2023, and June 30, 2025 6. At least one follow-up appointment during or after taking Ginkgo biloba

Exclusion criteria

Exclusion criteria: Patients who do not fullfill inclusion criteria

Design outcomes

Primary

MeasureTime frame
• Changes in neurocognitive symptoms, based on statements made by patients during medical interviews and a classification of symptoms on a three-point scale by the physician: o Deterioration o No change noticed o Slight improvement noticed o Significant improvement noticed

Secondary

MeasureTime frame
• Responders (noticed significant improvement vs. no significant improvement in neurocognitive symptoms) • Side effects of ginkgo biloba: occurrence and type of side effects or reasons for discontinuing ginkgo biloba • Use of new medications for fatigue or brain fog since baseline (e.g., antidepressants, aripiprazole, nootropics)

Countries

Germany

Contacts

Public ContactBenno Brinkhaus

Institut für Sozialmedizin, Epidemiologie und Gesundheitsökonomie, Charité Universitätsmedizin Berlin

benno.brinkhaus@charite.de004930450529002

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026