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Liquid biopsies for molecular precision diagnostics of pediatric cancers.

Liquid biopsies for molecular precision diagnostics of pediatric cancers.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038144
Enrollment
1000
Registered
2025-10-27
Start date
2026-01-21
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pediatric oncology

Interventions

Group 1: Analysis of liquid biopsy samples from a biobank blood samples of pediatric hematology-oncology patients at initial diagnosis.

Sponsors

Universitätsklinikum Heidelberg, Zentrum für Kinder- und Jugendmedizin, Klinik für Pädiatrische Onkologie, Hämatologie, Immunologie und Pneumologie
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Pediatric hemato-oncological patients who have been treated and/or are currently being treated at the Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, Im Neuenheimer Feld 430, 69120 Heidelberg. Only patients who have provided written consent for the use of residual materials within the framework of the biobank will be included.

Exclusion criteria

Exclusion criteria: Lack of consent or withdrawal of consent to participate in the biobank.

Design outcomes

Primary

MeasureTime frame
Is a minimally invasive, liquid biopsy–based determination of tumor entity possible at initial diagnosis?

Secondary

MeasureTime frame
Do liquid biopsies allow the identification of genetic alterations as targets for personalized therapies? What prognostic and predictive values can be derived from correlating clinical data (e.g., therapy response, tumor dissemination, outcome, etc.) with the molecular data obtained from the initial liquid biopsy?

Countries

Germany

Contacts

Public ContactFlorian Iser

Universitätsklinikum Heidelberg, Zentrum für Kinder- und Jugendmedizin, Klinik für Pädiatrische Onkologie, Hämatologie, Immunologie und Pneumologie

florian.iser@med.uni-heidelberg.de06221 56 311830

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026