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Questioning Binarity – Gender Diversity in Pain Medicine

Questioning Binarity – Gender Diversity in Pain Medicine

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038089
Enrollment
160
Registered
2025-12-03
Start date
2025-07-14
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gender-related differences in pain among cisgender and trans*gender individuals

Interventions

Group 1: The study examines healthy subjects of different genders. This includes cisgender individuals as well as transgender and non-binary individuals (e.g., nonbinary, genderfluid, or agender). Qua

Sponsors

UKSH Kiel, Klinik für Anästhesiologie und operative Intensivmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: healthy

Exclusion criteria

Exclusion criteria: Pregnancy, breastfeeding, pre-existing conditions affecting pain perception, skin injuries on the back of the hand or forearm, regular use of painkillers, use of intoxicants 72 hours prior to testing.

Design outcomes

Primary

MeasureTime frame
The aim of the study is to conduct a multifactorial investigation of the relationship between pain sensitivity and biopsychosocial gender components. This will be done at the hormonal level by measuring testosterone and estradiol levels, at the pain medicine level using Qualitative Sensory Testing (QST), Conditioned Pain Modulation (CPM), Cold Pressor Task (CPT), and psychosocially using the Hospital Anxiety and Depression Scale (HADS), Pain Catastrophizing Scale (PCS), Self-Efficacy Expectancy Scale (SWE), and German Extended Personal Attribute Questionnaire (GEPAQ). There is no endpoint in the conventional sense in this study.

Secondary

MeasureTime frame
Adjusted standard value proposal for trans patients to improve the care situation.

Countries

Germany

Contacts

Public ContactJanne Gierthmühlen

UKSH Kiel, Klinik für Anästhesiologie und operative Intensivmedizin

janne.gierthmuehlen@uksh.de043150020911

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026