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MAL RISK II: Risk of complications in outpatient treatment of imported Plasmodium falciparum malaria – an observational study in TropNet

MAL RISK II: Risk of complications in outpatient treatment of imported Plasmodium falciparum malaria – an observational study in TropNet - MAL RISK II

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00038051
Enrollment
2000
Registered
2025-10-07
Start date
2026-03-27
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

B50

Interventions

Group 1: Patients with confirmed Plasmodium falciparum malaria undergoing outpatient or inpatient treatment are or may be included in the study. The form of treatment and therapy is based on the stand

Sponsors

Charité - Universtitätsmedizin Berlin, Fächerverbund für Infektiologie, Pneumologie und Intensivmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Infection with Plasmodium falciparum

Exclusion criteria

Exclusion criteria: Patient cannot give informed consent due to physical or mental disability age <18 years

Design outcomes

Primary

MeasureTime frame
Proportion of patients infected with P. falciparum who are initially treated on an outpatient basis and who receive unscheduled medical care related to malaria or complications of malaria (including treatment complications) during the 28-day follow-up period.

Secondary

MeasureTime frame
Proportion of outpatients with at least one complication of malaria infection or malaria treatment during the 28-day follow-up period Proportion of outpatients with at least one hospitalization due to malaria infection or malaria treatment during the 28-day follow-up period Reasons for unplanned hospitalizations/admissions to identify risk factors for failure of outpatient treatment Proportion of patients still alive 28 days after starting treatment (for inpatients and outpatients) Comparison of clinical parameters and outcomes of inpatients with those of outpatients Investigation of clinical criteria relevant for hospital admission of patients with P. falciparum malaria in Europe

Countries

Belgium, Denmark, France, Germany, Italy, Netherlands, Norway, Spain, Switzerland, United Kingdom

Contacts

Public ContactTilman Lingscheid

Charité - Universtitätsmedizin Berlin, Fächerverbund für Infektiologie, Pneumologie und Intensivmedizin

tilman.lingscheid@charite.de+49 30 450 653 666

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026