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Conditions
Interventions
Group 1: Patients with left- or right hemisphere stroke are examined with linguistic and neuropsychological test instruments over the course of two test sessions of 60 minutes (on the same day or diff
Sponsors
Universität zu Lübeck
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Clinical groups: - Traumatic Brain Injury (moderate or severe by means of the Glasgow Coma Scale 1h), at least 4 weeks prior to testing - Stroke (unilateral, first onset, verified by radiology, hospital length of stay at least 2 days), at least 4 weeks prior to testing - German native speakers - sufficient visual and hearing abilities - suspected pragmatic disorder via a short screening - sufficient attention and vigilance functions for testing Healthy controls: - German native speakers - sufficient visual and hearing abilities
Exclusion criteria
Exclusion criteria: Clinical groups: - re. stroke: cerebellar, brain stem or bilateral stroke - prominent neglect - aphasia (according to patient file or formal testing) - other neurological or psychiatric disorder Healthy controls: - diagnosed neurological or psychiatric disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pragmatic abilities (especially discourse and figurative language) by means of the novel APACS-DE and their interactions with executive and socio-cognitive abilities, namely: - inferencing abilities measured by the MAKRO (Subtest Inferenzen) to validate the novel APACS-De - working memory by means of the Listening Span Task (German version) and the TAP (Subtest Arbeitsgedächtnis) - cognitive flexibility by means of the RWT (Regensburger Wortflüssigkeits-Test) and the M-WCST (modified Wisconsin Card Sorting Test) - inhibitory control by means of the TAP (Subtest Go/NoGo) - logical reasoning by means of the LPS (Leistungsprüfsystem, Subtest 3) - social emotion recognition by means of the COSIMO (Cognition of Social Interactions in Movies) - Theory of Mind by means of the SET (Story-based Empathy Task) An additional assessment of pragmatic abilities with the novel APACS-DE after 2-3 weeks enables verification of the reliability of the instrument. | — |
Secondary
| Measure | Time frame |
|---|---|
| Communication abilities rated by patients and their close others (by means of the LCQ, La Trobe Questionnaire) and subjective quality of life assessed by the patients (by means of the QOLIBRI) to allow evaluation of potential impact of pragmatic disabilities on daily functioning. Assessment of the FIM (Functional Independence Measure) allows for controlling for potential impact of functional disabilities. | — |
Countries
Germany, Switzerland
Contacts
Public ContactAnnette Baumgärtner
Universität zu Lübeck
Outcome results
None listed