No restriction to single diagnoses
Conditions
Interventions
Group 1: Geriatric patients with planned intensive care inpatient stays
Within this study, the following specific assessments will be performed:
Preoperative baseline (before ICU exposure):
Collecti
Sponsors
Klinik und Poliklinik für Altersmedizin, Universitätsmedizin Halle
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Scheduled elective surgery Planned postoperative ICU stay = 24 hours Capacity to provide informed consent (no acute delirium, no severe dementia) Written informed consent
Exclusion criteria
Exclusion criteria: Refusal to participate Acute delirium at the time of consent Severe dementia precluding informed consent and valid assessment (according to prior clinical diagnosis/documentation)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| predictive model for stable or improved HRQoL (EQ-5D-5L) at 3 and/or 6 months after ICU discharge relative to baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| To describe perioperative and post-ICU trajectories in physical, cognitive, and psychosocial domains at 3 and 6 months. To quantify rates of rehospitalisation, emergency visits, rehabilitation/nursing-home stays, and mortality within 6 months. To examine associations of SASP biomarkers and AGE skin autofluorescence with functional and HRQoL outcomes. To explore predictors of adverse events (e.g., decline in HRQoL, institutionalisation, death) for hypothesis generation. | — |
Countries
Germany
Contacts
Public ContactTino Prell
Klinik und Poliklinik für Altersmedizin, Universitätsmedizin Halle
Outcome results
None listed