F41.3/ F41.8/ F41.9 - basically, recurrent depressive and anxiety disorders will be treated in this study F33.1 F33.2 F33.9 F41.0 F41.1 F41.2 F33.0 F40.0 F40.1 F40.2
Conditions
Interventions
Group 1: Intervention Group (Process-Based Cognitive Behavioral Therapy
PB-CBT)
Pre-baseline assessment (questionnaires on psychopathology, well-being, and coping)
Including diagnostic interview through external diagnostician
Baseline EMA (Ecological Momentary Assessment):
Exploration and self-monitoring using intensive smartphone-based questionnaires, entered
individuals receive their personalized dynamic network model (network feedback), and the therapist receives feedback with personalized treatment recommendations (control-theoretically computed).
Colla
Post-network EMA assessment following completion of the 24 sessions. Including diagnostic interview through external diagnostician
Follow-up assessment, 3 months after end of treatment (questionnair
Sponsors
Philipps-Universität Marburg
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: main diagnosis of depressive or anxiety disorder (ICD-11) at least two guideline-oriented psychotherapeutic and/or pharmacologic treatments in the past (also if psychotherapy was combined with pharmacotherapy) - comorbidities are approved - sufficient german language skills - covered by a german statutory medical health insurance
Exclusion criteria
Exclusion criteria: Currently receiving ongoing psychotherapeutic treatment, acute suicidality, suicide attempt within the past three months, current alcohol/ substance dependence, primary diagnosis of post-traumatic stress disorder, lifetime diagnosis of Bipolar I disorder, current or past psychotic disorder, diagnosis of emotionally unstable personality disorder of borderline type, organic brain disorders, change in psychotropic medication within four weeks prior to study participation, serious medical conditions preventing participation in psychotherapy, psychiatric conditions requiring treatment in an alternative setting (e.g., BMI < 16.5).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Examination of effectiveness of network control theory- informed and process-based cognitive behavioral therapy (PB-KVT) (Hoffmann and Hayes, 2018) compared to guideline-oriented cognitive behavior therapy by default (r-KVT) in ambulant patients with difficult-to-treat unipolar depressions and anxiety disorders | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Depressive and anxiety symptoms in the intervention group will be significantly lower after the psychotherapeutic treatment compared to baseline. 2. Depressive and anxiety symptoms will be significantly lower in the intervention group compared to control group after the psychotherapeutic treatment. 3. Depressive and anxiety symptoms in the intervention group will be significantly lower three months after the psychotherapeutic treatment compared to baseline. 4. Quality of life, well-being, acceptance, reflective capacity, and functional inner processes in the intervention group will be significantly higher after the psychotherapeutic treatment compared to baseline. 5. Quality of life, well-being, acceptance, reflective capacity, and functional inner processes will be significantly higher in the intervention group compared to the control group after the psychotherapeutic treatment. 6. Quality of life, well-being, acceptance, reflective capacity, and functional inner processes in the intervention group will be significantly higher three months after the psychotherapeutic treatment compared to baseline. | — |
Countries
Germany
Contacts
Public ContactLucie Pahlen
Goethe-Universität Frankfurt am Main
Outcome results
None listed