High procalcitonin in gram-negative urosepsis: indicator of immune modulation rather than poor outcome

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00037950

Enrollment

300

Registered

2025-09-22

Start date

2017-07-15

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41 R65.2

Interventions

Group 1: In this study, three groups of septic patients are compared: patients with sepsis originating from a urinary, abdominal, or pulmonary infection focus. Correlations are examined between the pe

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Clinically confirmed sepsis according to Sepsis-3 guidelines with a known focus: urinary, abdominal, or pulmonary.

Exclusion criteria

Exclusion criteria: Patients with unknown sepsis focus, missing procalcitonin measurement, or missing prognostic scores.

Design outcomes

Primary

Measure	Time frame
sepsis severity indicators—SOFA score and peak lactate value	—

Secondary

Measure	Time frame
Intensive care unit (ICU) length of stay, ICU mortality, targeted microbiological analysis	—

Countries

Germany

Contacts

Public ContactSebastian Petzoldt

Klinik für Anästhesiologie, Operative Intensivmedizin und Schmerztherapie Universitätsklinikum Gießen und Marburg GmbH – Standort Gießen

Sebastian.Petzoldt@chiru.med.uni-giessen.de+49 641 986 56658

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 28, 2026