Children with familial hypercholesterolemia undergoing statin therapy E78.0
Conditions
Interventions
Group 1: Children with familial hypercholesterolemia undergoing statin therapy aged 6-18 years with one of their primary caregivers (parents)
Sponsors
Päd. Stoffwechselambulanz der Medizinische Hochschule Hannover
Eligibility
Sex/Gender
All
Age
6 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosed familial hypercholesterolemia or lipid metabolism disorder; Current and ongoing treatment with statins; Regular appointments at our lipid clinic; Presence of a parent or legal guardian who participates in the separate interview; Written declaration of consent (or consent of legal representatives in the case of minors)
Exclusion criteria
Exclusion criteria: Missing or incomplete written consent from minors or their legal representatives and parents; Children and adolescents who are not currently receiving statin therapy, as adherence perception is assessed in the context of ongoing therapy; Acute or serious illnesses (e.g., significant cognitive impairments or psychiatric disorders) that hinder reliable participation in the study and understanding of the questionnaires; Language barriers that prevent adequate responses to the standardized questionnaires and qualitative interviews; Parents who are not involved as primary caregivers in the daily therapy process
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in adherence assessment between children and parents, measured using validated questionnaires | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of subjective adherence values with objective laboratory parameters (e.g., LDL cholesterol); identification of specific barriers and facilitating factors in everyday family life through qualitative interviews; derivation of starting points for family-centered interventions based on the identified discrepancies and influencing factors. | — |
Countries
Germany
Contacts
Public ContactAnna Feest
Medizinische Hochschule Hannover
Outcome results
None listed