F90.0
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: A confirmed diagnosis of adult ADHD established during our outpatient clinic consultation
Exclusion criteria
Exclusion criteria: Limited ability of the patients to understand the participant information, provide informed consent, or comply with the study procedures. Physical illnesses that, due to their nature or severity, may interfere with the planned examinations or affect the parameters under investigation (e.g., focal organic brain disorders, severe visual impairment).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| There is a positive correlation between structural integration level and ADHD symptom severity. All patients in whom a diagnosis of adult ADHD was established according to guideline-based diagnostic procedures were included. Data collection was carried out using standardized questionnaires that have been established and validated in several studies: Structurla integration/ personality funktioning: OPD-SFK (Operationalized psychodynamic diagnostic - short version questionaire for psychic structure) LPFS-BF 2.0 (Levels of personality functioning - brief version) ADHD symptom severity: CAARS-K SB (Conners' Adult ADHD Rating Scales - short version self report) | — |
Secondary
| Measure | Time frame |
|---|---|
| Exploratory cross-sectional hypotheses: There is a negative correlation between structural integration level and everyday functional capacity. There is a negative correlation between structural integration level and quality of life. The structural integration level according to OPD-2 in our sample differs from that of the normative sample. The normative sample comes from a yet-to-be-published study by the OPD working group. Exploratory longitudinal hypotheses: Patients receiving polypharmaceutical psychopharmacological treatment (two or more medications) over the course of treatment differ from patients receiving only a single medication with respect to structural level. This would indicate that structural level may serve as an indicator of an increased risk for requiring polypharmaceutical psychopharmacological treatment (in cases of higher risk for insufficient symptom improvement under stimulant monotherapy). There is a negative correlation between OPD structural level and improvement in ADHD symptom severity (difference in scores between the first and second assessment time points). There is a positive correlation between OPD structural level and improvement in quality of life during treatment (difference in scores between the first and second assessment time points). There is a positive correlation between OPD structural level and improvement in functional capacity during treatment (difference in scores between the first and second assessment time points). Assessment Baseline assessment: Conducted at the time of presentation to the ADHD consultation service. Follow-up assessment: Conducted 12 weeks (± 1 week) after initiation of pharmacotherapy with stimulants. Instruments Quality of life: Adult ADHD Quality of Life (AAQoL). Functional impairment in daily life: Weiss Functional Impairment Rating Scale – Self Report (WFIRS-S). Instruments used to assess clinical characteristics of the sample: Patient Health Questionnaire-9 (PHQ-9) | — |
Countries
Germany
Contacts
SHK, Charité